Molecular and Developmental Genetics
Office: 240 Padnos
Phone: (616) 331-2471
Ph.D. in Biochemistry & Biophysics; University of North Carolina, Chapel Hill, 1994.
B.S. in Biology; Kent State University, 1983.
Courses Taught at GVSU:
BIO 120 General Biology I
BIO 328 Biomedical Ethics
BIO 355 Human Genetics
BIO 376 Genetics Laboratory
BIO 405 Cell and Molecular Biology
BIO 406 Cell & Molecular Biology Laboratory
Dr. Sass’ current research involves her favorite experimental organism, the fruit fly Drosophila melanogaster. She is using the well-studied process of oogenesis to determine the molecular components that are required to establish a functional egg. She is studying a unique gain-of-function mutation that disrupts cell-cell signaling between germ-line derived cells and somatic cells of an egg chamber during oogenesis. Characterizations of this mutation, as well as genetic analysis of its interaction with proteins known to function in this pathway, are currently underway.
Sass GL, Pannuti A, Lucchesi JC. Male-specific lethal complex of Drosophila targets activated regions of the X chromosome for chromatin remodeling. Proc Natl Acad Sci. USA. 2003 Jul 8;100(14):8287-91.
Sass GL, Henikoff S. Pairing-dependent mislocalization of a Drosophila brown gene reporter to a heterochromatic environment. Genetics. 1999 Jun;152(2):595-604.
Sass GL, Henikoff S. Comparative analysis of position-effect variegation mutations in Drosophila melanogaster delineates the targets of modifiers. Genetics. 1998 Feb;148(2):733-41.
Sass GL, Comer AR, Searles LL. The ovarian tumor protein isoforms of Drosophila melanogaster exhibit differences in function, expression, and localization. Dev Biol. 1995 Jan;167(1):201-12.
Sass GL, Mohler JD, Walsh RC, Kalfayan LJ, Searles LL. Structure and expression of hybrid dysgenesis-induced alleles of the ovarian tumor (otu) gene in Drosophila melanogaster. Genetics. 1993 Feb;133(2):253-63.
Page last modified March 12, 2014